Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 18/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17483990 | 0.86 | HDAC1 (0.52) | HDAC1HDAC2HDAC3HDAC6RARB | |
| SCHEMBL17483982 | 0.80 | HDAC1 (0.59) | HDAC1HDAC2HDAC3HDAC6RARB | |
| SCHEMBL4580381 | 0.79 | HDAC1 (0.66) | HDAC1HDAC2HDAC3 | |
| SCHEMBL4580375 | 0.79 | HDAC1 (0.66) | HDAC1HDAC2HDAC3 | |
| SCHEMBL2133626 | 0.78 | HDAC1 (0.61) | HDAC1HDAC2HDAC3HDAC8 | |
| SCHEMBL2133614 | 0.78 | HDAC1 (0.61) | HDAC1HDAC2HDAC3HDAC8 | |
| SCHEMBL2402836 | 0.76 | HDAC1 (0.77) | HDAC1HDAC2HDAC3HDAC6HDAC8 | |
| SCHEMBL2402840 | 0.76 | HDAC1 (0.77) | HDAC1HDAC2HDAC3HDAC6HDAC8 | |
| SCHEMBL17483930 | 0.75 | HDAC1 (0.54) | HDAC1HDAC2HDAC3 | |
| SCHEMBL1067187 | 0.74 | HDAC1 (0.56) | HDAC1HDAC2HDAC3HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016018795-A1 | HISTONE DEACETYLASE INHIBITORS | THE GENERAL HOSPITAL CORPORATION (US) | 2016-02-04 | — | — | WO | disclosed |