Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 11/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.32 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | GPR183 | P32249 | 1/20 | 0.32 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17484352 | 0.96 | S1PR1 (0.35) | S1PR1S1PR3RARBTSHRTNNC1 | |
| SCHEMBL17484354 | 0.95 | TSHR (0.39) | S1PR1S1PR3TSHRTNNC1SGPL1 | |
| SCHEMBL17484457 | 0.94 | RARB (0.34) | S1PR1S1PR3RARBTSHRTHRA | |
| SCHEMBL17484197 | 0.94 | TSHR (0.34) | S1PR1S1PR3RARBTSHRTHRB | |
| SCHEMBL17484460 | 0.93 | S1PR1 (0.35) | S1PR1S1PR3RARBTSHRTHRB | |
| SCHEMBL17484382 | 0.91 | S1PR1 (0.34) | S1PR1S1PR3RARBTSHRTHRB | |
| SCHEMBL17484195 | 0.91 | S1PR1 (0.35) | S1PR1S1PR3RARBTSHRTHRB | |
| SCHEMBL17484458 | 0.87 | S1PR1 (0.38) | S1PR1S1PR3RARBS1PR4S1PR5 | |
| SCHEMBL17484201 | 0.87 | S1PR1 (0.37) | S1PR1S1PR3RARBTHRB | |
| SCHEMBL17484454 | 0.86 | RARB (0.36) | RARBTSHRTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3174955-B1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2019-10-23 | — | — | EP | disclosed |
| US-10294426-B2 | Liquid crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2019-05-21 | — | — | US | disclosed |
| US-20180208848-A1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | disclosed |
| US-20180208848-A1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | disclosed |
| WO-2016015803-A1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2016-02-04 | — | — | WO | disclosed |