Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 9/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | VDR | P11473 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17484378 | 0.95 | S1PR1 (0.38) | S1PR1S1PR3POLBAPEX1HTT | |
| SCHEMBL17484438 | 0.93 | S1PR1 (0.40) | S1PR1S1PR3POLBAPEX1HTT | |
| SCHEMBL17484460 | 0.91 | S1PR1 (0.35) | S1PR1S1PR3POLBAPEX1HTT | |
| SCHEMBL17484195 | 0.89 | S1PR1 (0.35) | S1PR1S1PR3POLBAPEX1HTT | |
| SCHEMBL17484458 | 0.89 | S1PR1 (0.38) | S1PR1S1PR3POLBAPEX1HTT | |
| SCHEMBL17484439 | 0.88 | S1PR1 (0.39) | S1PR1S1PR3POLBAPEX1HTT | |
| SCHEMBL20412536 | 0.88 | POLB (0.40) | S1PR1S1PR3POLBAPEX1HTT | |
| SCHEMBL17484382 | 0.88 | S1PR1 (0.34) | S1PR1S1PR3POLBAPEX1HTT | |
| SCHEMBL17477156 | 0.86 | POLB (0.41) | S1PR1S1PR3POLBAPEX1HTT | |
| SCHEMBL17484390 | 0.86 | POLB (0.37) | S1PR1S1PR3POLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3174955-B1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2019-10-23 | — | — | EP | disclosed |
| US-10294426-B2 | Liquid crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2019-05-21 | — | — | US | disclosed |
| US-20180208848-A1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | disclosed |
| US-20180208848-A1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | disclosed |
| WO-2016015803-A1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2016-02-04 | — | — | WO | disclosed |