Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17484361 | 0.96 | S1PR1 (0.40) | S1PR1S1PR3POLBAPEX1HTT | |
| SCHEMBL17484388 | 0.94 | S1PR1 (0.40) | S1PR1S1PR3POLBAPEX1HTT | |
| SCHEMBL17484384 | 0.90 | S1PR1 (0.40) | S1PR1S1PR3POLBAPEX1HTT | |
| SCHEMBL17484360 | 0.87 | POLB (0.38) | S1PR1POLBAPEX1HTTTDP1 | |
| SCHEMBL17484358 | 0.87 | POLB (0.38) | S1PR1POLBAPEX1HTTTDP1 | |
| SCHEMBL17484382 | 0.87 | S1PR1 (0.34) | S1PR1S1PR3POLBAPEX1HTT | |
| SCHEMBL17484195 | 0.85 | S1PR1 (0.35) | S1PR1S1PR3POLBAPEX1HTT | |
| SCHEMBL17484362 | 0.85 | POLB (0.35) | S1PR1POLBAPEX1HTTTDP1 | |
| SCHEMBL17484359 | 0.85 | POLB (0.35) | S1PR1POLBAPEX1HTTTDP1 | |
| SCHEMBL17484381 | 0.84 | TSHR (0.35) | S1PR1S1PR3POLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3174955-B1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2019-10-23 | — | — | EP | disclosed |
| US-10294426-B2 | Liquid crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2019-05-21 | — | — | US | disclosed |
| US-20180208848-A1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | disclosed |
| US-20180208848-A1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | disclosed |
| WO-2016015803-A1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2016-02-04 | — | — | WO | disclosed |