Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 9/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10020856 | 0.93 | RARB (0.44) | RARBPPARAS1PR1S1PR3CYP4A11 | |
| SCHEMBL17484462 | 0.93 | RARB (0.42) | RARBPPARAS1PR1S1PR3FFAR1 | |
| SCHEMBL15357798 | 0.92 | RARB (0.53) | RARBS1PR1S1PR3FAAHPTGS2 | |
| SCHEMBL15121729 | 0.89 | RARB (0.42) | RARBS1PR1S1PR3FFAR1FAAH | |
| SCHEMBL15468765 | 0.88 | FFAR1 (0.42) | RARBS1PR1S1PR3FFAR1FFAR4 | |
| SCHEMBL17484407 | 0.88 | RARB (0.42) | RARBS1PR1S1PR3FFAR1FAAH | |
| SCHEMBL18194858 | 0.87 | RARB (0.40) | RARBS1PR1S1PR3FFAR1FFAR4 | |
| SCHEMBL17484412 | 0.86 | RARB (0.35) | RARBPPARAS1PR1S1PR3CYP4A11 | |
| SCHEMBL9607902 | 0.86 | ELANE (0.48) | PTGS2APPCYP2C19ELANE | |
| SCHEMBL10020925 | 0.85 | PPARA (0.48) | RARBPPARACYP4A11PTGS2ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3174955-B1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2019-10-23 | — | — | EP | disclosed |
| US-10294426-B2 | Liquid crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2019-05-21 | — | — | US | disclosed |
| US-20180208848-A1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | disclosed |
| US-20180208848-A1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | disclosed |
| WO-2016015803-A1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2016-02-04 | — | — | WO | disclosed |