Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | AGER | Q15109 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1303181 | 0.89 | KDM4E (0.54) | KDM4EL3MBTL1ATMPOLBALDH1A1 | |
| SCHEMBL29389255 | 0.89 | KDM4E (0.54) | KDM4EL3MBTL1ATMPOLBALDH1A1 | |
| SCHEMBL24609436 | 0.85 | KDM4E (0.50) | KDM4EL3MBTL1ATMPOLBALDH1A1 | |
| SCHEMBL29623840 | 0.79 | KDM4E (0.45) | KDM4EL3MBTL1ATMPOLBALDH1A1 | |
| SCHEMBL24522165 | 0.79 | KDM4E (0.45) | KDM4EL3MBTL1ATMPOLBALDH1A1 | |
| SCHEMBL19849289 | 0.79 | KDM4E (0.45) | KDM4EL3MBTL1ATMPOLBALDH1A1 | |
| SCHEMBL23373491 | 0.79 | KDM4E (0.45) | KDM4EL3MBTL1ATMPOLBALDH1A1 | |
| SCHEMBL17051451 | 0.79 | KDM4E (0.45) | KDM4EL3MBTL1ATMPOLBGPR3 | |
| SCHEMBL31650776 | 0.79 | KDM4E (0.45) | KDM4EL3MBTL1ATMPOLBALDH1A1 | |
| SCHEMBL11892606 | 0.79 | KDM4E (0.45) | KDM4EL3MBTL1ATMPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016015815-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2016-02-04 | — | — | WO | disclosed |