Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 10/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.51 |
| ▸ | ELANE | P08246 | 3/20 | 0.50 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17488506 | 1.00 | KCNH2 (0.65) | KCNH2CYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL17490823 | 0.96 | KCNH2 (0.70) | KCNH2CYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL18648212 | 0.96 | KCNH2 (0.70) | KCNH2CYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL17490819 | 0.96 | KCNH2 (0.70) | KCNH2CYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL12034446 | 0.92 | KCNH2 (0.74) | KCNH2CYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL204291 | 0.91 | KCNH2 (0.64) | KCNH2CYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL2706552 | 0.91 | KCNH2 (0.64) | KCNH2CYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL15127355 | 0.89 | KCNH2 (0.60) | KCNH2CYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL12620507 | 0.89 | KCNH2 (0.61) | KCNH2CYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL12599764 | 0.89 | KCNH2 (0.61) | KCNH2CYP3A4CYP2C9NR1I2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9598362-B2 | Benzidine derivative, method for preparing same, and pharmaceutical composition containing benzidine derivative for treating liver disease caused by hepatitis C virus | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2017-03-21 | — | — | US | disclosed |
| US-20160031810-A1 | BENZIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING BENZIDINE DERIVATIVE FOR TREATING LIVER DISEASE CAUSED BY HEPATITIS C VIRUS | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2016-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160031810-A1 | BENZIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING BENZIDINE DERIVATIVE FOR TREATING LIVER DISEASE CAUSED BY HEPATITIS C VIRUS | ODC1, HAVCR2, PBDC1 | KCNH2 385/4885CYP3A4 261/4885CYP2C9 160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.