Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.52 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2389818 | 0.92 | TLR7 (0.52) | TLR7TLR8 | |
| SCHEMBL2385776 | 0.87 | TLR7 (0.61) | TLR7TLR8 | |
| SCHEMBL2387720 | 0.83 | TLR7 (0.52) | TLR7TLR8 | |
| SCHEMBL2389803 | 0.82 | TLR7 (0.54) | TLR7TLR8 | |
| SCHEMBL12048715 | 0.82 | TLR7 (0.62) | TLR7 | |
| SCHEMBL2387060 | 0.82 | TLR7 (0.58) | TLR7 | |
| SCHEMBL2388328 | 0.82 | TLR7 (0.53) | TLR7TLR8 | |
| SCHEMBL12048758 | 0.81 | TLR7 (0.65) | TLR7 | |
| SCHEMBL2389142 | 0.81 | TLR7 (0.55) | TLR7TLR8 | |
| SCHEMBL2388302 | 0.79 | TLR7 (0.57) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1728793-B1 | 9-SUBSTITUTED 8-OXOADENINE COMPOUND | SUMITOMO DAINIPPON PHARMA CO LTD (JP) | 2016-02-03 | — | — | EP | disclosed |