Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 18/20 | 0.56 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17493997 | 0.83 | AAK1 (0.56) | AAK1TAAR1 | |
| SCHEMBL17515823 | 0.80 | AAK1 (0.84) | AAK1TAAR1 | |
| SCHEMBL17515994 | 0.79 | AAK1 (0.85) | AAK1TAAR1 | |
| SCHEMBL17493870 | 0.79 | AAK1 (0.81) | AAK1TAAR1 | |
| SCHEMBL17515955 | 0.78 | AAK1 (0.84) | AAK1TAAR1 | |
| Hydrochloric Acid SCHEMBL19328169 | 0.78 | AAK1 (0.80) | AAK1TAAR1 | |
| SCHEMBL17493773 | 0.78 | AAK1 (0.85) | AAK1TAAR1 | |
| SCHEMBL17493951 | 0.76 | AAK1 (0.54) | AAK1TAAR1 | |
| SCHEMBL17494137 | 0.76 | AAK1 (0.83) | AAK1TAAR1 | |
| SCHEMBL17494140 | 0.76 | AAK1 (0.83) | AAK1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3177604-A1 | HETEROCYCLIC KINASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2017-06-14 | — | — | EP | disclosed |
| WO-2016022312-A1 | HETEROCYCLIC KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-02-11 | — | — | WO | disclosed |