Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 9/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17495184 | 0.99 | MCHR1 (0.34) | MCHR1HRH4AXLACACBMTNR1A | |
| Trifluoroacetic Acid SCHEMBL17495181 | 0.95 | HRH4 (0.36) | MCHR1HRH4 | |
| SCHEMBL14757038 | 0.88 | HRH4 (0.38) | MCHR1HRH4AXL | |
| Hydrochloric Acid SCHEMBL14745588 | 0.87 | HRH4 (0.37) | MCHR1HRH4AXL | |
| SCHEMBL17494898 | 0.86 | HRH4 (0.32) | MCHR1HRH4 | |
| Hydrochloric Acid SCHEMBL17593324 | 0.82 | KCNH2 (0.36) | MCHR1HRH4 | |
| SCHEMBL17495070 | 0.80 | KCNH2 (0.38) | MCHR1 | |
| Hydrochloric Acid SCHEMBL18628245 | 0.75 | HRH4 (0.36) | MCHR1HRH4AXL | |
| SCHEMBL14757183 | 0.75 | KCNH2 (0.40) | MCHR1 | |
| SCHEMBL17536064 | 0.75 | EGLN1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016025932-A1 | SUBSTITUTED POLYCYCLIC ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-02-18 | — | — | WO | claimed |
| WO-2016025932-A1 | SUBSTITUTED POLYCYCLIC ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-02-18 | — | — | WO | disclosed |
| WO-2016025932-A1 | SUBSTITUTED POLYCYCLIC ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-02-18 | — | — | WO | disclosed |