Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17494928 | 0.88 | KDM4E (0.35) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL17498163 | 0.74 | USP2 (0.45) | USP2KDM4EHTTGAAMEN1 | |
| SCHEMBL17494909 | 0.70 | — | — | |
| SCHEMBL17495040 | 0.70 | KDR (0.31) | — | |
| SCHEMBL17536033 | 0.68 | KDM4E (0.36) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL14741226 | 0.67 | MPL (0.35) | KDM4EHTTMEN1ALDH1A1KMT2A | |
| SCHEMBL17536102 | 0.67 | VHL (0.39) | KDM4EHTTMEN1ALDH1A1HPGD | |
| SCHEMBL17495115 | 0.66 | KDM4E (0.35) | KDM4EMAOBMEN1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL17495111 | 0.65 | — | — | |
| SCHEMBL17495057 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016025932-A1 | SUBSTITUTED POLYCYCLIC ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-02-18 | — | — | WO | disclosed |