Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17495293 | 0.91 | HCRTR1 (0.56) | HCRTR1HCRTR2 | |
| SCHEMBL1398755 | 0.89 | HCRTR1 (0.59) | HCRTR1HCRTR2 | |
| SCHEMBL1398757 | 0.89 | HCRTR1 (0.59) | HCRTR1HCRTR2 | |
| SCHEMBL16277711 | 0.86 | HCRTR1 (0.71) | HCRTR1HCRTR2 | |
| SCHEMBL15173477 | 0.86 | HCRTR1 (0.71) | HCRTR1HCRTR2 | |
| SCHEMBL17009311 | 0.86 | HCRTR1 (0.71) | HCRTR1HCRTR2 | |
| SCHEMBL16277594 | 0.86 | HCRTR1 (0.71) | HCRTR1HCRTR2 | |
| SCHEMBL20040294 | 0.86 | HCRTR1 (0.71) | HCRTR1HCRTR2 | |
| SCHEMBL15184281 | 0.86 | HCRTR1 (0.71) | HCRTR1HCRTR2 | |
| SCHEMBL16282484 | 0.86 | HCRTR1 (0.71) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3180332-A1 | DIFLUOROPYRROLIDINES AS OREXIN RECEPTOR MODULATORS | Eolas Therapeutics Inc. (US) | 2017-06-21 | — | — | EP | disclosed |
| WO-2016025669-A1 | DIFLUOROPYRROLIDINES AS OREXIN RECEPTOR MODULATORS | EOLAS THERAPEUTICS, INC. (US) | 2016-02-18 | — | — | WO | disclosed |