Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17498097 | 0.99 | KDM4E (0.33) | KDM4EALDH1A1HPGDENPP2HSD17B10 | |
| SCHEMBL30914222 | 0.76 | — | — | |
| SCHEMBL17498195 | 0.74 | KDM4E (0.33) | KDM4EALDH1A1HPGDENPP2HSD17B10 | |
| Hydrochloric Acid SCHEMBL17498096 | 0.73 | KDM4E (0.33) | KDM4EALDH1A1HPGDENPP2HSD17B10 | |
| SCHEMBL11580679 | 0.68 | TSHR (0.33) | ALDH1A1 | |
| SCHEMBL11580681 | 0.68 | TSHR (0.33) | ALDH1A1 | |
| SCHEMBL3412825 | 0.60 | TP53 (0.30) | — | |
| SCHEMBL15330778 | 0.60 | TP53 (0.30) | — | |
| SCHEMBL6422575 | 0.60 | F7 (0.43) | KDM4EALDH1A1HPGDENPP2HSD17B10 | |
| SCHEMBL27209675 | 0.59 | TSHR (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016025933-A2 | SUBSTITUTED POLYCYCLIC ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-02-18 | — | — | WO | claimed |
| WO-2016025933-A2 | SUBSTITUTED POLYCYCLIC ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-02-18 | — | — | WO | disclosed |