Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CTH | P32929 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095532 | 0.88 | MEN1 (0.48) | MEN1KMT2AHTR1ADRD2POLB | |
| SCHEMBL16097026 | 0.88 | POLB (0.34) | MEN1KMT2AHTR1ADRD2POLB | |
| SCHEMBL16097024 | 0.88 | POLB (0.34) | MEN1KMT2AHTR1ADRD2POLB | |
| SCHEMBL17499557 | 0.86 | NR4A1 (0.39) | MEN1KMT2AHTR1ADRD2POLB | |
| SCHEMBL17499584 | 0.83 | SLC6A2 (0.33) | MEN1KMT2A | |
| SCHEMBL16095976 | 0.83 | ABCB1 (0.33) | ABCB1 | |
| SCHEMBL17499215 | 0.81 | TAAR1 (0.42) | MEN1KMT2AHTR1ADRD2POLB | |
| SCHEMBL16097198 | 0.81 | ABCB1 (0.36) | HTR1ADRD2ABCB1 | |
| SCHEMBL17499796 | 0.81 | — | — | |
| SCHEMBL17499252 | 0.80 | CA1 (0.41) | MEN1KMT2ALMNAL3MBTL1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |