Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16101254 | 0.88 | CYP2C9 (0.34) | CYP2C9TSHRCYP2C19MTORHRH4 | |
| SCHEMBL16101325 | 0.85 | CYP2C9 (0.32) | CYP2C9TSHRCYP2C19MTORHRH4 | |
| SCHEMBL17499307 | 0.83 | TSHR (0.33) | CYP2C9TSHRCYP2C19MTORHRH4 | |
| SCHEMBL17499099 | 0.83 | CYP2C9 (0.34) | CYP2C9TSHRCYP2C19MTORHRH4 | |
| SCHEMBL17499403 | 0.79 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL17499405 | 0.79 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL16097423 | 0.79 | SCN8A (0.42) | CYP2C9TSHRHRH3 | |
| SCHEMBL17499542 | 0.79 | CYP2C9 (0.33) | CYP2C9TSHRCYP2C19MTORHRH4 | |
| SCHEMBL17499746 | 0.78 | CYP2C9 (0.32) | CYP2C9TSHRCYP2C19MTORHRH4 | |
| SCHEMBL16096761 | 0.77 | SCN4A (0.33) | CYP2C9TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |