Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499245 | 1.00 | GRIN1 (0.32) | GRIN1GRIN2BALDH1A1MEN1KMT2A | |
| SCHEMBL16096567 | 0.87 | GRIN1 (0.33) | GRIN1GRIN2BALDH1A1MEN1KMT2A | |
| SCHEMBL16096568 | 0.87 | GRIN1 (0.33) | GRIN1GRIN2BALDH1A1MEN1KMT2A | |
| SCHEMBL17499317 | 0.87 | BCHE (0.32) | ALDH1A1HPGDGLA | |
| SCHEMBL16095748 | 0.86 | GRIN1 (0.42) | GRIN1GRIN2BALDH1A1MEN1KMT2A | |
| SCHEMBL17499661 | 0.86 | GRIN1 (0.42) | GRIN1GRIN2BALDH1A1MEN1KMT2A | |
| SCHEMBL17499119 | 0.85 | GRIN1 (0.32) | GRIN1GRIN2BALDH1A1MEN1KMT2A | |
| SCHEMBL17499117 | 0.85 | GRIN1 (0.32) | GRIN1GRIN2BALDH1A1MEN1KMT2A | |
| SCHEMBL17499200 | 0.84 | KDM4E (0.31) | GRIN1GRIN2BALDH1A1MEN1KMT2A | |
| SCHEMBL16102898 | 0.84 | KDM4E (0.31) | GRIN1GRIN2BALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |