N-Furfurylidene-O-Anisidine

N-Furfurylidene-O-Anisidine

SCHEMBL17499541

COc1ccccc1N=Cc1ccco1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.58
ALDH1A1 P00352 10/20 0.58
MEN1 O00255 7/20 0.58
KMT2A Q03164 7/20 0.58
KDM4E B2RXH2 5/20 0.58
GAA P10253 4/20 0.58
HSD17B10 Q99714 3/20 0.45
L3MBTL1 Q9Y468 3/20 0.45
NPSR1 Q6W5P4 2/20 0.45
MAPK1 P28482 2/20 0.45
ALOX15 P16050 2/20 0.45
TSHR P16473 1/20 0.45
ALOX12 P18054 1/20 0.45
ATM Q13315 1/20 0.45
ESR2 Q92731 1/20 0.45
HPGD P15428 3/20 0.44
SENP7 Q9BQF6 1/20 0.44
LMNA P02545 2/20 0.44
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
N-Furfurylidene-O-Anisidine SCHEMBL17499539 1.00 MAPT (0.58) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL17499286 0.84 MAPT (0.55) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL17499289 0.84 MAPT (0.55) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL17499591 0.83 MAPT (0.54) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL16095556 0.82 MAPT (0.75) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL16095557 0.82 MAPT (0.75) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL16096645 0.82 MAPT (0.49) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL16095859 0.82 MAPT (0.49) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL16096643 0.82 MAPT (0.49) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL16095858 0.82 MAPT (0.49) MAPTALDH1A1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9850328-B2 Polymers functionalized with heterocyclic imines BRIDGESTONE CORPORATION (JP) 2017-12-26 US disclosed
US-20160039958-A1 Polymers Functionalized With Heterocyclic Imines BRIDGESTONE CORPORATION (JP) 2016-02-11 US disclosed