Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 9/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17500329 | 0.90 | KDM4E (0.51) | KDM4EALOX15HSD17B10PDE5AHDAC1 | |
| SCHEMBL19161235 | 0.90 | KDM4E (0.51) | KDM4EALOX15HSD17B10PDE5AHDAC1 | |
| SCHEMBL17500286 | 0.90 | KDM4E (0.51) | KDM4EALOX15HSD17B10PDE5AHDAC1 | |
| SCHEMBL17520562 | 0.90 | KDM4E (0.51) | KDM4EALOX15HSD17B10PDE5AHDAC1 | |
| SCHEMBL17500285 | 0.90 | KDM4E (0.51) | KDM4EALOX15HSD17B10PDE5AHDAC1 | |
| SCHEMBL24012054 | 0.90 | KDM4E (0.51) | KDM4EALOX15HSD17B10PDE5AHDAC1 | |
| Hydrochloric Acid SCHEMBL17500248 | 0.89 | KDM4E (0.50) | KDM4EALOX15HSD17B10PDE5AHDAC1 | |
| Hydrochloric Acid SCHEMBL17500246 | 0.89 | KDM4E (0.50) | KDM4EALOX15HSD17B10PDE5AHDAC1 | |
| Hydrochloric Acid SCHEMBL17500318 | 0.89 | KDM4E (0.50) | KDM4EALOX15HSD17B10PDE5AHDAC1 | |
| Hydrochloric Acid SCHEMBL17500247 | 0.89 | KDM4E (0.50) | KDM4EALOX15HSD17B10PDE5AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3177621-A1 | NOVEL HDAC6 INHIBITORS AND THEIR USES | Universität Regensburg (DE) | 2017-06-14 | — | — | EP | disclosed |
| WO-2016020369-A1 | NOVEL HDAC6 INHIBITORS AND THEIR USES | UNIVERSITÄT REGENSBURG (DE) | 2016-02-11 | — | — | WO | disclosed |