SCHEMBL175020

SCHEMBL175020

Brc1cnc(Br)s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL256074 0.78 SNCA (0.52)
SCHEMBL344676 0.73
SCHEMBL8445365 0.73
SCHEMBL3564958 0.73
Bromide SCHEMBL145295 0.71
Bromide SCHEMBL8465585 0.69
SCHEMBL10140459 0.69
SCHEMBL2018856 0.69
SCHEMBL23396003 0.69
SCHEMBL856844 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 933 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117157792-A Flame retardant for battery electrolyte 雅宝公司 2023-12-01 CN claimed
CN-114759196-B Conjugated microporous polymer electrocatalyst loaded with metal nano particles and preparation method and application thereof 青岛大学 2023-08-29 CN claimed
JP-63205316-A None JP disclosed
EP-4731216-A1 HETEROARYL-AMINE COMPOUNDS AND USE THEREOF AS HDAC6 INHIBITORS Augustine Therapeutics (BE) 2026-04-29 EP disclosed
CN-121873105-A 2-Isopropyl-5- (4, 5-tetramethyl-1, 3, 2-dioxaborolan-2-yl) thiazole and synthetic method and application thereof 凯美克(上海)医药科技有限公司 2026-04-17 CN disclosed
EP-4696316-A2 RAS INHIBITORS Revolution Medicines, Inc. (US) 2026-02-18 EP disclosed
US-20260042759-A1 INHIBITOR CONTAINING BICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF SHANGHAI HANSOH BIOMEDICAL CO LTD (CN) 2026-02-12 US disclosed
US-20260042740-A1 RAS INHIBITORS REVOLUTION MEDICINES INC (US) 2026-02-12 US disclosed
EP-4054719-B1 RAS INHIBITORS REVOLUTION MEDICINES INC (US) 2026-02-11 EP disclosed
US-12522593-B2 Azacycloalkyl carbonyl cyclic amine compound ALIVEXIS, INC. (JP) 2026-01-13 US disclosed
WO-2025245175-A1 MACROCYCLIC HETEROAROMATIC INHIBITORS OF JAK2 AJAX THERAPEUTICS, INC. (US) 2025-11-27 WO disclosed
EP-0555068-A1 Oxime derivatives as 5-lipoxygenase inhibitors ZENECA LIMITED (GB) 1993-08-11 EP disclosed
US-5030727-A Reacting an anthronilide derivative with a thiazole derivative or a fluorozuinazolone with a neucleophile BASF AKTIENGESELLSCHAFT (DE) 1991-07-09 US disclosed
US-4892678-A DOPED WITH AN ANION; SEMICONDUCTOR AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY, MINISTRY OF INTERNATIONAL TRADE & INDUSTRY (JP) 1990-01-09 US disclosed
US-4877852-A SEMICONDUCTOR MATERIALS AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1989-10-31 US disclosed
JP-S63205316-A ORGANIC SEMICONDUCTOR AGENCY OF IND SCIENCE & TECHNOL 1988-08-24 JP disclosed
EP-0263523-A2 Process for the preparation of thiazolo [2,3-b] quinazolones BASF Aktiengesellschaft (DE) 1988-04-13 EP disclosed
US-4089865-A Certain thiazole compounds SYNTEX (U.S.A.) INC. (US) 1978-05-16 US disclosed
US-4001421-A THIAZOLE CARDIOVASCULAR AGENTS SYNTEX (U.S.A.) INC. (US) 1977-01-04 US disclosed
US-3982010-A Thiazole cardiovascular agents SYNTEX (U.S.A.) INC. (US) 1976-09-21 US disclosed