Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1A | P54750 | 8/20 | 0.79 |
| ▸ | PDE1B | Q01064 | 4/20 | 0.79 |
| ▸ | PDE4A | P27815 | 12/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14158337 | 0.92 | PDE1A (0.80) | PDE1APDE1BPDE4A | |
| SCHEMBL17508443 | 0.90 | PDE1A (0.79) | PDE1APDE1BPDE4A | |
| SCHEMBL17508439 | 0.90 | PDE1A (0.64) | PDE1APDE1BPDE4A | |
| SCHEMBL17610009 | 0.88 | PDE1A (0.77) | PDE1APDE1BPDE4A | |
| SCHEMBL14242884 | 0.88 | PDE1A (1.00) | PDE1APDE1BPDE4A | |
| SCHEMBL14243126 | 0.87 | PDE1A (1.00) | PDE1APDE1BPDE4A | |
| SCHEMBL7516708 | 0.86 | PDE1A (0.72) | PDE1APDE1BPDE4A | |
| SCHEMBL17508448 | 0.86 | PDE1A (0.72) | PDE1APDE1BPDE4A | |
| SCHEMBL19447761 | 0.82 | PDE1A (0.66) | PDE1APDE1BPDE4A | |
| SCHEMBL19447765 | 0.81 | PDE1A (0.64) | PDE1APDE1BPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3177627-A1 | ORGANIC COMPOUNDS | Intra-Cellular Therapies, Inc. (US) | 2017-06-14 | — | — | EP | disclosed |
| WO-2016022893-A1 | ORGANIC COMPOUNDS | INTRA-CELLULAR THERAPIES, INC. (US) | 2016-02-11 | — | — | WO | disclosed |