SCHEMBL17514580

SCHEMBL17514580

Fc1[c]ccc(-c2c(F)cc(F)cc2F)c1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17514911 0.84 ESR1 (0.31) ESR1ESR2
SCHEMBL17514507 0.84 ESR1 (0.31) ESR1ESR2
SCHEMBL15636751 0.83 TTR (0.37)
SCHEMBL2061683 0.82
SCHEMBL17514885 0.80 ESR1 (0.32) ESR1ESR2
SCHEMBL17514814 0.80 EGLN2 (0.35) ESR1ESR2
SCHEMBL7861005 0.79
SCHEMBL17514587 0.76
SCHEMBL27959529 0.76 ESR1 (0.31) ESR1ESR2
SCHEMBL533230 0.74 BCL2L1 (0.35) ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016026830-A1 NOVEL FUNGICIDAL PYRAZOLE DERIVATIVES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-02-25 WO disclosed