Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 5/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.35 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21736817 | 0.80 | MAOB (0.39) | NPC1RAB9ATP53MAPTSMN1; SMN2 | |
| SCHEMBL15985642 | 0.79 | MAOB (0.40) | NPC1RAB9ATP53MAPTSMN1; SMN2 | |
| SCHEMBL17514886 | 0.79 | KAT6A (0.38) | NPC1RAB9ATP53MAPTSMN1; SMN2 | |
| SCHEMBL4733374 | 0.77 | MEN1 (0.39) | MAPTSMN1; SMN2MEN1LMNAKMT2A | |
| SCHEMBL21718878 | 0.76 | MAOB (0.39) | NPC1RAB9ATP53MAPTSMN1; SMN2 | |
| SCHEMBL4677175 | 0.76 | MEN1 (0.39) | NPC1RAB9ATP53MAPTSMN1; SMN2 | |
| SCHEMBL24595108 | 0.75 | KAT6A (0.40) | NPC1RAB9ATP53MAPTSMN1; SMN2 | |
| SCHEMBL17514649 | 0.74 | KAT6A (0.40) | MAPTSMN1; SMN2MEN1LMNAKMT2A | |
| SCHEMBL17514486 | 0.74 | MEN1 (0.37) | MAPTSMN1; SMN2MEN1LMNAKMT2A | |
| SCHEMBL21728091 | 0.74 | TAAR1 (0.41) | NPC1RAB9AMAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016026830-A1 | NOVEL FUNGICIDAL PYRAZOLE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-02-25 | — | — | WO | disclosed |