SCHEMBL17514869

SCHEMBL17514869

N#Cc1cc(F)c(-c2cc(Cl)[c]cc2F)c(F)c1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EGLN2 Q96KS0 2/20 0.32
TRPV4 Q9HBA0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17514803 0.89 EGLN2 (0.31) EGLN2
SCHEMBL17515016 0.83 EGLN2 (0.33) EGLN2
SCHEMBL17514558 0.80
SCHEMBL17514494 0.80 MEN1 (0.32) EGLN2
SCHEMBL17514665 0.80 EGLN2 (0.34) EGLN2
SCHEMBL17514823 0.77
SCHEMBL17514586 0.77
SCHEMBL17514800 0.77 EGLN2 (0.32) EGLN2
SCHEMBL17515023 0.75 EGLN2 (0.31) EGLN2
SCHEMBL17514867 0.75 EGLN2 (0.31) EGLN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016026830-A1 NOVEL FUNGICIDAL PYRAZOLE DERIVATIVES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-02-25 WO disclosed