SCHEMBL17514928

SCHEMBL17514928

C#CC(Oc1cc[c]cc1)c1cccc(Cl)c1

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 3/20 0.32
GAA P10253 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
AOC3 Q16853 1/20 0.32
ACP3 P15309 1/20 0.32
SLC6A2 P23975 2/20 0.30
SLC6A3 Q01959 2/20 0.30
CYP2D6 P10635 1/20 0.30
ADRB2 P07550 1/20 0.30
ADRB3 P13945 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11086531 0.86 SLC6A4 (0.43) SLC6A4MEN1KMT2AAOC3ACP3
SCHEMBL17515003 0.82 IDO1 (0.36) SLC6A4AOC3
SCHEMBL17514691 0.81 SLC6A2 (0.32) SLC6A4TDP1SLC6A2SLC6A3
SCHEMBL17514966 0.80 EPAS1 (0.31)
SCHEMBL17514722 0.80 SLC6A2 (0.32) SLC6A4SLC6A2SLC6A3CYP2D6
SCHEMBL17514749 0.79 IDO1 (0.40) SLC6A4MEN1KMT2AACP3SLC6A2
SCHEMBL17514878 0.78
SCHEMBL7004930 0.78 ACP3 (0.35) SLC6A4GAAMEN1KMT2AAOC3
SCHEMBL17514598 0.77 SLC6A4 (0.39) SLC6A4SLC6A2SLC6A3CYP2D6
SCHEMBL5546380 0.77 SLC6A4 (0.45) SLC6A4AOC3ADRB2ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016026830-A1 NOVEL FUNGICIDAL PYRAZOLE DERIVATIVES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-02-25 WO disclosed