Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8158740 | 0.88 | ERN1 (0.44) | ERN1ALOX15ALOX12NQO2MAPT | |
| SCHEMBL19468429 | 0.80 | NQO2 (0.44) | ERN1ALOX15ALOX12NQO2MAPT | |
| SCHEMBL15821778 | 0.78 | ERN1 (0.38) | ERN1ALOX15ALOX12NQO2MAPT | |
| SCHEMBL16269387 | 0.78 | ERN1 (0.38) | ERN1ALOX15ALOX12NQO2MAPT | |
| SCHEMBL16345333 | 0.78 | ERN1 (0.55) | ERN1ALOX15ALOX12APPLMNA | |
| SCHEMBL28702635 | 0.78 | HTR2A (0.38) | MAPTNPSR1POLBL3MBTL1HTR1A | |
| SCHEMBL31034989 | 0.74 | ERN1 (0.64) | ERN1ALOX15MAPTALDH1A1CYP1A2 | |
| SCHEMBL31035696 | 0.74 | ERN1 (0.35) | ERN1ALOX15ALOX12NQO2MAPT | |
| SCHEMBL19607137 | 0.73 | HSD17B10 (0.45) | ALOX15ALOX12MAPTTUBB4ATUBB | |
| SCHEMBL1000103 | 0.73 | MAPT (0.58) | ERN1ALOX15ALOX12NQO2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016022312-A1 | HETEROCYCLIC KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-02-11 | — | — | WO | disclosed |