Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17663481 | 0.90 | AAK1 (0.57) | AAK1IMPDH2 | |
| SCHEMBL17493948 | 0.87 | AAK1 (0.78) | AAK1IMPDH2 | |
| SCHEMBL17515950 | 0.86 | AAK1 (0.61) | AAK1 | |
| SCHEMBL17515977 | 0.86 | AAK1 (0.73) | AAK1 | |
| SCHEMBL17515824 | 0.85 | AAK1 (0.58) | AAK1IMPDH2 | |
| SCHEMBL17515986 | 0.84 | AAK1 (0.77) | AAK1 | |
| SCHEMBL17515826 | 0.83 | AAK1 (0.67) | AAK1 | |
| SCHEMBL17516059 | 0.81 | AAK1 (0.86) | AAK1 | |
| SCHEMBL17663450 | 0.81 | AAK1 (0.61) | AAK1IMPDH2 | |
| SCHEMBL17515829 | 0.81 | AAK1 (1.00) | AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170260145-A1 | HETEROCYCLIC KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-09-14 | — | — | US | disclosed |
| WO-2016022312-A1 | HETEROCYCLIC KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-02-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170260145-A1 | HETEROCYCLIC KINASE INHIBITORS | AAK1, NCK1, DAPK2 | AAK1 1/4885IMPDH2 3681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.