Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17517356 | 0.95 | GUCY1A1 (0.34) | GUCY1A1GUCY1B1 | |
| SCHEMBL17517363 | 0.93 | GUCY1A1 (0.30) | GUCY1A1GUCY1B1 | |
| SCHEMBL17517355 | 0.88 | GUCY1A1 (0.34) | GUCY1A1GUCY1B1 | |
| SCHEMBL17517360 | 0.88 | GUCY1A1 (0.39) | GUCY1A1GUCY1B1 | |
| SCHEMBL17517354 | 0.88 | — | — | |
| SCHEMBL17517357 | 0.83 | GUCY1A1 (0.43) | GUCY1A1GUCY1B1 | |
| SCHEMBL17517367 | 0.82 | KCNH2 (0.41) | GUCY1A1GUCY1B1 | |
| SCHEMBL17517365 | 0.77 | KCNH2 (0.40) | GUCY1A1GUCY1B1 | |
| SCHEMBL12364302 | 0.73 | KCNH2 (0.49) | GUCY1A1GUCY1B1 | |
| SCHEMBL12364301 | 0.71 | KCNH2 (0.55) | GUCY1A1GUCY1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160122347-A1 | 4,6-DIAMINOPYRIMIDINE STIMULATORS OF SOLUBLE GUANYLATE CYCLASE | AUSPEX PHARMACEUTICALS INC (US) | 2016-05-05 | — | — | US | disclosed |
| US-9260424-B2 | 4,6-diaminopyrimidine stimulators of soluble guanylate cyclase | AUSPEX PHARMACEUTICALS, INC. (US) | 2016-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160122347-A1 | 4,6-DIAMINOPYRIMIDINE STIMULATORS OF SOLUBLE GUANYLATE CYCLASE | GUCY1B2, GUCY1A2, GUCY1A1 | GUCY1A1 3/4885GUCY1B1 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.