⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18869 | 0.58 | — | — | |
| SCHEMBL13965289 | 0.56 | — | — | |
| SCHEMBL2808209 | 0.56 | — | — | |
| SCHEMBL13350280 | 0.56 | — | — | |
| SCHEMBL8248285 | 0.56 | — | — | |
| SCHEMBL1101703 | 0.54 | — | — | |
| SCHEMBL32680463 | 0.50 | — | — | |
| SCHEMBL22580336 | 0.50 | — | — | |
| SCHEMBL2162034 | 0.50 | — | — | |
| SCHEMBL208338 | 0.50 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780039-B1 | CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF | PFIZER (US) | 2017-11-29 | — | — | EP | disclosed |
| US-20160039911-A1 | TEMPERATURE SHIFT FOR HIGH YIELD EXPRESSION OF POLYPEPTIDES IN YEAST AND OTHER TRANSFORMED CELLS | H. LUNDBECK A/S (DK) | 2016-02-11 | — | — | US | disclosed |