Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17504920 | 1.00 | NR1H3 (1.00) | NR1H3NR1H2 | |
| SCHEMBL21433369 | 0.86 | NR1H2 (0.76) | NR1H3NR1H2 | |
| SCHEMBL21433372 | 0.86 | NR1H2 (0.76) | NR1H3NR1H2 | |
| SCHEMBL17505005 | 0.86 | NR1H2 (1.00) | NR1H3NR1H2 | |
| SCHEMBL17519286 | 0.86 | NR1H2 (1.00) | NR1H3NR1H2 | |
| SCHEMBL17519340 | 0.85 | NR1H3 (0.81) | NR1H3NR1H2 | |
| SCHEMBL17504954 | 0.85 | NR1H2 (1.00) | NR1H3NR1H2 | |
| SCHEMBL19214380 | 0.85 | NR1H3 (0.81) | NR1H3NR1H2 | |
| SCHEMBL17504984 | 0.85 | NR1H3 (0.81) | NR1H3NR1H2 | |
| SCHEMBL17519285 | 0.85 | NR1H2 (1.00) | NR1H3NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106715413-B | piperazine derivatives as liver X receptor modulators | VITAE PHARMACEUTICALS, INC. (US) | 2019-11-01 | — | — | CN | disclosed |
| US-20170226067-A1 | PIPERAZINE DERIVATIVES AS LIVER X RECEPTOR MODULATORS | VITAE PHARMACEUTICALS, INC. (US) | 2017-08-10 | — | — | US | disclosed |
| CN-106715413-A | Piperazine derivatives as liver x receptor modulators | 生命医药公司 | 2017-05-24 | — | — | CN | disclosed |
| WO-2016022521-A1 | PIPERAZINE DERIVATIVES AS LIVER X RECEPTOR MODULATORS | VITAE PHARMACEUTICALS, INC. (US) | 2016-02-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170226067-A1 | PIPERAZINE DERIVATIVES AS LIVER X RECEPTOR MODULATORS | NR1H2, NR1H3, NR1I2 | NR1H3 2/4885NR1H2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.