SCHEMBL17520332

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11132	1.00	EGFR (1.00)	EGFRKDREPHB4EPHA2CIT
	SCHEMBL8669	0.99	EGFR (1.00)	EGFRKDREPHB4EPHA2CIT
	SCHEMBL12012	0.96	EGFR (1.00)	EGFRKDREPHB4EPHA2CIT
	SCHEMBL17520338	0.96	EGFR (1.00)	EGFRKDREPHB4EPHA2CIT
	SCHEMBL11395	0.95	EGFR (1.00)	EGFRKDREPHB4EPHA2CIT
	SCHEMBL17520333	0.95	EGFR (0.95)	EGFRKDREPHB4EPHA2CIT
	SCHEMBL8949	0.94	EGFR (1.00)	EGFRKDREPHB4EPHA2CIT
	SCHEMBL11019	0.92	EGFR (1.00)	EGFRKDREPHB4EPHA2CIT
	SCHEMBL907931	0.92	KDR (1.00)	EGFRKDREPHB4EPHA2ERBB2
	SCHEMBL906652	0.91	KDR (1.00)	EGFRKDREPHB4EPHA2ERBB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.