Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 17/20 | 0.82 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19138925 | 1.00 | HDAC6 (0.82) | HDAC6ENPP2HDAC1HDAC4HDAC2 | |
| SCHEMBL19139010 | 0.93 | HDAC6 (0.82) | HDAC6ENPP2HDAC1HDAC4HDAC2 | |
| SCHEMBL19138981 | 0.91 | HDAC6 (0.83) | HDAC6ENPP2HDAC1HDAC4HDAC2 | |
| SCHEMBL17520423 | 0.90 | HDAC6 (1.00) | HDAC6ENPP2HDAC1HDAC4HDAC2 | |
| SCHEMBL17520547 | 0.89 | HDAC6 (0.77) | HDAC6ENPP2HDAC1HDAC4HDAC2 | |
| SCHEMBL19138959 | 0.89 | HDAC6 (0.81) | HDAC6ENPP2HDAC1HDAC4HDAC2 | |
| SCHEMBL19168584 | 0.89 | HDAC6 (0.81) | HDAC6ENPP2HDAC1HDAC4HDAC2 | |
| SCHEMBL19161147 | 0.86 | HDAC6 (0.82) | HDAC6ENPP2HDAC1HDAC4HDAC2 | |
| SCHEMBL19138902 | 0.86 | HDAC6 (0.82) | HDAC6ENPP2HDAC1HDAC4HDAC2 | |
| SCHEMBL19161261 | 0.84 | HDAC6 (0.82) | HDAC6ENPP2HDAC1HDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016020369-A1 | NOVEL HDAC6 INHIBITORS AND THEIR USES | UNIVERSITÄT REGENSBURG (DE) | 2016-02-11 | — | — | WO | disclosed |