SCHEMBL17520598 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	HDAC6	Q9UBN7	20/20	0.69

▸	HDAC2	Q92769	16/20	0.67

▸	HDAC8	Q9BY41	15/20	0.67

▸	HDAC3	O15379	3/20	0.57

▸	HDAC1	Q13547	3/20	0.57

▸	HDAC4	P56524	1/20	0.57

▸	HDAC7	Q8WUI4	1/20	0.57

▸	HDAC10	Q969S8	1/20	0.57

▸	HDAC11	Q96DB2	1/20	0.57

▸	HDAC5	Q9UQL6	1/20	0.57

▸	NCOR2	Q9Y618	1/20	0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL19138926	0.93	HDAC6 (0.73)	HDAC6HDAC2HDAC8HDAC3HDAC1
SCHEMBL19167615	0.90	HDAC6 (0.69)	HDAC6HDAC2HDAC8HDAC3HDAC1
SCHEMBL19138946	0.89	HDAC6 (0.85)	HDAC6HDAC2HDAC8HDAC3HDAC1
SCHEMBL19139014	0.87	HDAC6 (0.66)	HDAC6HDAC2HDAC8HDAC3HDAC1
SCHEMBL20634170	0.87	HDAC6 (0.82)	HDAC6HDAC2HDAC8HDAC3HDAC1
SCHEMBL24012096	0.87	HDAC6 (0.62)	HDAC6HDAC2HDAC8HDAC3HDAC1
SCHEMBL19138892	0.86	HDAC6 (0.71)	HDAC6HDAC2HDAC8HDAC3HDAC1
SCHEMBL19138908	0.86	HDAC6 (0.71)	HDAC6HDAC2HDAC8HDAC3HDAC1
SCHEMBL22467821	0.85	HDAC6 (0.85)	HDAC6HDAC2HDAC8HDAC3HDAC1
SCHEMBL22467790	0.85	HDAC6 (0.85)	HDAC6HDAC2HDAC8HDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2016020369-A1	NOVEL HDAC6 INHIBITORS AND THEIR USES	UNIVERSITÄT REGENSBURG (DE)	2016-02-11	—	—	WO	disclosed