Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 18/20 | 0.78 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.68 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.68 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.68 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.68 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.68 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19138902 | 0.92 | HDAC6 (0.82) | HDAC6HDAC1HDAC4HDAC2HDAC10 | |
| SCHEMBL19161147 | 0.92 | HDAC6 (0.82) | HDAC6HDAC1HDAC4HDAC2HDAC10 | |
| SCHEMBL19161149 | 0.88 | HDAC6 (1.00) | HDAC6HDAC1HDAC4HDAC2HDAC10 | |
| SCHEMBL19138993 | 0.88 | HDAC6 (1.00) | HDAC6HDAC1HDAC4HDAC2HDAC10 | |
| SCHEMBL17520635 | 0.86 | HDAC6 (0.76) | HDAC6HDAC1HDAC4HDAC2HDAC10 | |
| SCHEMBL19162239 | 0.85 | HDAC6 (0.83) | HDAC6HDAC1HDAC4HDAC2HDAC10 | |
| SCHEMBL19138897 | 0.85 | HDAC6 (0.83) | HDAC6HDAC1HDAC4HDAC2HDAC10 | |
| SCHEMBL19138998 | 0.83 | HDAC6 (0.83) | HDAC6HDAC1HDAC4HDAC2HDAC10 | |
| SCHEMBL19162242 | 0.83 | HDAC6 (0.83) | HDAC6HDAC1HDAC4HDAC2HDAC10 | |
| SCHEMBL19169226 | 0.83 | HDAC6 (0.70) | HDAC6HDAC1HDAC4HDAC2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016020369-A1 | NOVEL HDAC6 INHIBITORS AND THEIR USES | UNIVERSITÄT REGENSBURG (DE) | 2016-02-11 | — | — | WO | disclosed |