Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 20/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.59 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19166544 | 0.83 | HDAC6 (0.57) | HDAC6HDAC1HDAC10HDAC2HDAC8 | |
| SCHEMBL23718128 | 0.82 | HDAC6 (0.69) | HDAC6HDAC1HDAC10HDAC2HDAC8 | |
| SCHEMBL20634777 | 0.79 | HDAC6 (0.58) | HDAC6HDAC1HDAC10HDAC2HDAC8 | |
| SCHEMBL23815860 | 0.79 | HDAC6 (0.58) | HDAC6HDAC1HDAC10HDAC2HDAC8 | |
| SCHEMBL24012013 | 0.75 | HDAC6 (0.68) | HDAC6HDAC1HDAC10HDAC2HDAC8 | |
| SCHEMBL1052951 | 0.75 | HDAC6 (1.00) | HDAC6HDAC1HDAC10HDAC2HDAC8 | |
| SCHEMBL24011868 | 0.75 | HDAC6 (0.57) | HDAC6HDAC1HDAC10HDAC2HDAC8 | |
| SCHEMBL24011743 | 0.73 | HDAC6 (0.58) | HDAC6HDAC1HDAC10HDAC2HDAC8 | |
| Tubastatin A SCHEMBL29356061 | 0.73 | HDAC6 (1.00) | HDAC6HDAC1HDAC10HDAC2HDAC8 | |
| Tubastatin A SCHEMBL1057119 | 0.73 | HDAC6 (1.00) | HDAC6HDAC1HDAC10HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016020369-A1 | NOVEL HDAC6 INHIBITORS AND THEIR USES | UNIVERSITÄT REGENSBURG (DE) | 2016-02-11 | — | — | WO | disclosed |