Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cyclohexane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 3/20 | 0.70 |
| ▸ | LCK | P06239 | 1/20 | 0.70 |
| ▸ | FYN | P06241 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cycloheptane SCHEMBL4093676 | 1.00 | FFAR3 (0.70) | FFAR3LCKFYNLMNATSHR | |
| Cycloheptane SCHEMBL2012782 | 1.00 | FFAR3 (0.70) | FFAR3LCKFYNLMNATSHR | |
| Cyclohexane SCHEMBL6561216 | 1.00 | FFAR3 (0.70) | FFAR3LCKFYNLMNATSHR | |
| Cyclopentane SCHEMBL1506252 | 1.00 | — | — | |
| Cyclohexane SCHEMBL11040391 | 1.00 | FFAR3 (0.70) | FFAR3LCKFYNLMNATSHR | |
| Cyclohexane SCHEMBL2060004 | 1.00 | FFAR3 (0.70) | FFAR3LCKFYNLMNATSHR | |
| Cyclohexane SCHEMBL7737259 | 1.00 | FFAR3 (0.70) | FFAR3LCKFYNLMNATSHR | |
| Cyclohexane SCHEMBL482428 | 1.00 | FFAR3 (0.70) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL1396702 | 1.00 | — | — | |
| Cyclohexane SCHEMBL2060015 | 1.00 | FFAR3 (0.70) | FFAR3LCKFYNLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-220478148-U | Comprehensive utilization system for hydrogen in cyclohexanone device by esterification method | 湖南百利工程科技股份有限公司 | 2024-02-13 | — | — | CN | claimed |
| CN-117050009-A | Preparation method of 4-trifluoromethyl pyridine intermediate core parent nucleus and derivatives thereof | 台州臻挚生物科技有限公司 | 2023-11-14 | — | — | CN | claimed |
| CN-117024859-A | Wet masterbatch and preparation method thereof | 青岛黑猫新材料研究院有限公司 | 2023-11-10 | — | — | CN | claimed |
| CN-116637386-A | Comprehensive utilization system and process method for hydrogen in cyclohexanone device by esterification method | 湖南百利工程科技股份有限公司 | 2023-08-25 | — | — | CN | claimed |
| CN-111087495-B | Hydrogenation catalyst for producing hydrogenated styrene-conjugated diene copolymer, method for producing hydrogenation catalyst, hydrogenation method, and hydrogenated copolymer | 中国石油化工股份有限公司 | 2023-03-14 | — | — | CN | claimed |
| CN-111085269-B | Hydrogenation catalyst for preparing cyclopentene by cyclopentadiene hydrogenation, preparation method and hydrogenation method thereof | 中国石油化工股份有限公司 | 2023-03-14 | — | — | CN | claimed |
| CN-111085273-B | Hydrogenation catalyst for preparing cyclopentene by cyclopentadiene hydrogenation, preparation method and hydrogenation method thereof | 中国石油化工股份有限公司 | 2023-02-28 | — | — | CN | claimed |
| CN-108593806-A | A kind of Chinese medicine residual harmful substance cloud point extraction solid phase detection methods | 河南福瑞滋生物科技有限公司 | 2018-09-28 | — | — | CN | claimed |
| CN-106473142-A | One kind improves women sleep, delays the health food of female middle-aged ovarian-senescence | 江西中天医药生物有限公司 | 2017-03-08 | — | — | CN | claimed |
| CN-103880598-B | A kind of method of coproduction hexalin and ethanol and device | SINOPEC CORP. (CN) | 2016-04-27 | — | — | CN | claimed |
| US-6221367-B1 | EXPOSING A BIOLOGICALLY ACTIVE AGENT TO A COMPLEXING PERTURBANT TO REVERSIBLY TRANSFORM THE BIOLOGICALLY ACTIVE AGENT TO THE INTERMEDIATE STATE AND TO FORM A TRANSPORTABLE SUPRAMOLECULAR COMPLEX | EMISPHERE TECHNOLOGIES, INC. | 2001-04-24 | — | — | US | claimed |
| EP-0969822-A2 | COMPOSITIONS AND METHODS FOR RESTORING A NORMAL PATTERN OF IMPRINTING TO CELLS | THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 2000-01-12 | — | — | EP | claimed |
| WO-1998029108-A2 | COMPOSITIONS AND METHODS FOR RESTORING A NORMAL PATTERN OF IMPRINTING TO CELLS | THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 1998-07-09 | — | — | WO | claimed |
| EP-0479471-B1 | Corrosion-inhibited antifreeze/coolant composition containing cyclohexane acid | TEXACO DEVELOPMENT CORP (US) | 1996-02-28 | — | — | EP | claimed |
| CN-1116199-A | Process for preparing carbonate esters | NIPPON CATALYTIC CHEM IND (JP) | 1996-02-07 | — | — | CN | claimed |
| CN-1108651-A | Substituted 1-naphthyl-3-pyrazolecarboxamides which are actie on neurotensin, their preparation and pharmaceutical compositions containing them | SANOFI SA (FR) | 1995-09-20 | — | — | CN | claimed |
| CN-1072405-A | Preparation method of cyclohexyl acetate | CHANGCHUN APPLIED CHEMISTRY (CN) | 1993-05-26 | — | — | CN | claimed |
| EP-0479471-A1 | Corrosion-inhibited antifreeze/coolant composition containing cyclohexane acid | TEXACO DEVELOPMENT CORPORATION (US) | 1992-04-08 | — | — | EP | claimed |
| US-5085791-A | Corrosion-inhibited antifreeze/coolant composition containing cyclohexane acid(s) | TEXACO CHEMICAL COMPANY (US) | 1992-02-04 | — | — | US | claimed |
| US-4272511-A | POLYMER OF VINYLPYRROLIDONE, VINYL ACETATE, CROTONIC ACID AND AT LEAST ONE OTHER MONOMER | L'OREAL (FR) | 1981-06-09 | — | — | US | claimed |