Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | L3MBTL3 | Q96JM7 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | MBTD1 | Q05BQ5 | 2/20 | 0.34 |
| ▸ | TP53BP1 | Q12888 | 2/20 | 0.34 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.33 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22144481 | 0.85 | CHRM3 (0.58) | CHRM3L3MBTL3L3MBTL1OPRM1OPRD1 | |
| SCHEMBL7539678 | 0.73 | CRBN (0.42) | OPRM1OPRD1OPRK1OGFRL1CRBN | |
| SCHEMBL22119758 | 0.72 | CHRM3 (0.42) | CHRM3L3MBTL3L3MBTL1AKR1C3GFER | |
| SCHEMBL17525016 | 0.72 | CHRM3 (0.38) | CHRM3L3MBTL3L3MBTL1GFERCRBN | |
| SCHEMBL22144449 | 0.72 | CHRM3 (0.57) | CHRM3L3MBTL3L3MBTL1GFERMBTD1 | |
| SCHEMBL17525115 | 0.72 | CHRM3 (0.35) | CHRM3L3MBTL3L3MBTL1AKR1C3GFER | |
| SCHEMBL17525017 | 0.72 | CHRM3 (0.37) | CHRM3L3MBTL3L3MBTL1GFERCHRNA1 | |
| SCHEMBL17525071 | 0.72 | IDH1 (0.38) | CHRM3ALDH1A1KMT2A | |
| SCHEMBL15701568 | 0.71 | CHRM2 (0.45) | CHRM3L3MBTL1OPRM1OPRD1OPRK1 | |
| SCHEMBL17524897 | 0.70 | CHRM3 (0.36) | CHRM3L3MBTL3L3MBTL1GFERMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016022644-A1 | HETEROCYCLIC CGRP RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME CORP. (US) | 2016-02-11 | — | — | WO | disclosed |