Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24258419 | 0.85 | GABRR1 (0.30) | GABRR1 | |
| SCHEMBL16507954 | 0.77 | — | — | |
| SCHEMBL17733762 | 0.77 | — | — | |
| SCHEMBL19632776 | 0.77 | GABRR1 (0.32) | GABRR1 | |
| SCHEMBL12464598 | 0.71 | GABRR1 (0.32) | GABRR1 | |
| SCHEMBL19143417 | 0.71 | GABRR1 (0.32) | GABRR1 | |
| SCHEMBL20411720 | 0.70 | — | — | |
| SCHEMBL21241804 | 0.69 | — | — | |
| SCHEMBL12320547 | 0.67 | — | — | |
| SCHEMBL17525135 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016020288-A1 | OPTIONALLY FUSED HETEROCYCLYL-SUBSTITUTED DERIVATIVES OF PYRIMIDINE USEFUL FOR THE TREATMENT OF INFLAMMATORY, METABOLIC, ONCOLOGIC AND AUTOIMMUNE DISEASES | NUEVOLUTION A/S (DK) | 2016-02-11 | — | — | WO | disclosed |