Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5910757 | 0.97 | HRH3 (0.57) | HRH3MAPTCYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL17526234 | 0.95 | HRH3 (0.55) | HRH3MAPTCYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL5910804 | 0.95 | HRH3 (0.62) | HRH3MAPTCYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL17495643 | 0.86 | HRH3 (0.46) | HRH3MAPTCYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL25477672 | 0.86 | HRH3 (0.46) | HRH3MAPTCYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL7106726 | 0.84 | HRH3 (0.50) | HRH3MAPTCYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL2844514 | 0.84 | HRH3 (0.50) | HRH3MAPTCYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL17526229 | 0.84 | HRH3 (0.48) | HRH3MAPTCYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL17528500 | 0.83 | HRH3 (0.46) | HRH3MAPTSIGMAR1CARM1PRMT6 | |
| SCHEMBL17526221 | 0.83 | HRH3 (0.46) | HRH3MAPTSIGMAR1CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016020137-A1 | NITROGEN-CONTAINING COMPOUNDS SUITABLE FOR USE IN THE PRODUCTION OF POLYURETHANES | EVONIK DEGUSSA GMBH (DE) | 2016-02-11 | — | — | WO | disclosed |