Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 20/20 | 0.63 |
| ▸ | CSNK1D | P48730 | 15/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16701075 | 1.00 | CSNK1E (0.63) | CSNK1ECSNK1D | |
| SCHEMBL16711255 | 1.00 | CSNK1E (0.63) | CSNK1ECSNK1D | |
| SCHEMBL17527265 | 0.90 | CSNK1E (0.56) | CSNK1ECSNK1D | |
| SCHEMBL17527264 | 0.90 | CSNK1E (0.56) | CSNK1ECSNK1D | |
| SCHEMBL16711510 | 0.90 | CSNK1E (0.56) | CSNK1ECSNK1D | |
| SCHEMBL16699217 | 0.90 | CSNK1E (0.67) | CSNK1ECSNK1D | |
| SCHEMBL16700006 | 0.89 | CSNK1E (0.58) | CSNK1ECSNK1D | |
| SCHEMBL16711301 | 0.89 | CSNK1E (0.58) | CSNK1ECSNK1D | |
| SCHEMBL16700004 | 0.89 | CSNK1E (0.58) | CSNK1ECSNK1D | |
| SCHEMBL21131232 | 0.88 | CSNK1E (0.70) | CSNK1ECSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9273058-B2 | Substituted pyrazolo-piperazines as casein kinase 1 δ/ε inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-03-01 | — | — | US | claimed |
| EP-3068785-B1 | SUBSTITUTED 4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRAZINE DERIVATIVES AS CASEIN KINASE 1 D/E INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2019-06-26 | — | — | EP | disclosed |