Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXER1 | Q8TDS5 | 4/20 | 0.54 |
| ▸ | FPR2 | P25090 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.48 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 4/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3406687 | 1.00 | OXER1 (0.54) | OXER1FPR2ALDH1A1LTB4R2LTB4R | |
| SCHEMBL3411397 | 1.00 | OXER1 (0.54) | OXER1FPR2ALDH1A1LTB4R2LTB4R | |
| SCHEMBL16675136 | 1.00 | OXER1 (0.54) | OXER1FPR2ALDH1A1LTB4R2LTB4R | |
| SCHEMBL3406682 | 1.00 | OXER1 (0.54) | OXER1FPR2ALDH1A1LTB4R2LTB4R | |
| SCHEMBL12151577 | 1.00 | OXER1 (0.54) | OXER1FPR2ALDH1A1LTB4R2LTB4R | |
| SCHEMBL3404679 | 1.00 | OXER1 (0.54) | OXER1FPR2ALDH1A1LTB4R2LTB4R | |
| SCHEMBL20085622 | 1.00 | OXER1 (0.54) | OXER1FPR2ALDH1A1LTB4R2LTB4R | |
| SCHEMBL16675135 | 1.00 | OXER1 (0.54) | OXER1FPR2ALDH1A1LTB4R2LTB4R | |
| SCHEMBL3406717 | 1.00 | OXER1 (0.54) | OXER1FPR2ALDH1A1LTB4R2LTB4R | |
| SCHEMBL16677125 | 0.95 | OXER1 (0.53) | OXER1FPR2ALDH1A1LTB4R2LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3037401-A2 | 14-HYDROXY-DOCOSAHEXAENOIC ACID COMPOUNDS | The Brigham And Women's Hospital Inc. (US) | 2016-06-29 | — | — | EP | disclosed |
| EP-2344441-B1 | 7,14-DIHYDROXY-DOCOSAHEXAENOIC ACID COMPOUNDS | BRIGHAM & WOMENS HOSPITAL (US) | 2016-02-17 | — | — | EP | disclosed |