Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | APEX1 | P27695 | 2/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22449554 | 1.00 | MAPT (0.44) | MAPTNR1I2PPARGALBSLC22A6 | |
| SCHEMBL3111744 | 0.93 | MAPT (0.43) | MAPTNR1I2PPARGALBSLC22A6 | |
| SCHEMBL3111746 | 0.93 | MAPT (0.43) | MAPTNR1I2PPARGALBSLC22A6 | |
| SCHEMBL19707205 | 0.93 | MAPT (0.43) | MAPTNR1I2PPARGALBSLC22A6 | |
| SCHEMBL17897722 | 0.92 | MAPT (0.42) | MAPTNR1I2PPARGALBSLC22A6 | |
| SCHEMBL12968453 | 0.84 | CTDSP1 (0.39) | MAPTNR1I2PPARGALBSLC22A6 | |
| SCHEMBL9173651 | 0.84 | TDP1 (0.49) | MAPTNR1I2PPARGALBSLC22A6 | |
| SCHEMBL21307548 | 0.83 | NR1I2 (0.56) | MAPTNR1I2PPARGALBSLC22A6 | |
| SCHEMBL12968958 | 0.83 | NR1I2 (0.56) | MAPTNR1I2PPARGALBSLC22A6 | |
| SCHEMBL17528943 | 0.83 | NR1I2 (0.56) | MAPTNR1I2PPARGALBSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016025839-A1 | SYNTHESIS OF CEPHALOSPORIN COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2016-02-18 | — | — | WO | disclosed |