Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 20/20 | 0.55 |
| ▸ | PIK3CD | O00329 | 12/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 11/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 11/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17529071 | 0.95 | PIK3CB (0.57) | PIK3CBPIK3CDPIK3CAPIK3CG | |
| SCHEMBL17529045 | 0.95 | PIK3CB (0.57) | PIK3CBPIK3CDPIK3CAPIK3CG | |
| SCHEMBL15029964 | 0.93 | PIK3CB (0.60) | PIK3CBPIK3CDPIK3CAPIK3CG | |
| SCHEMBL16308210 | 0.90 | PIK3CB (0.58) | PIK3CBPIK3CDPIK3CAPIK3CG | |
| SCHEMBL16308101 | 0.89 | PIK3CB (0.50) | PIK3CBPIK3CDPIK3CAPIK3CG | |
| SCHEMBL16308120 | 0.89 | PIK3CB (0.50) | PIK3CBPIK3CDPIK3CAPIK3CG | |
| SCHEMBL16308233 | 0.88 | PIK3CB (0.54) | PIK3CBPIK3CDPIK3CAPIK3CG | |
| SCHEMBL16308148 | 0.87 | PIK3CB (0.55) | PIK3CBPIK3CDPIK3CAPIK3CG | |
| SCHEMBL17529053 | 0.87 | PIK3CB (0.48) | PIK3CBPIK3CDPIK3CAPIK3CG | |
| SCHEMBL15030006 | 0.87 | PIK3CB (0.54) | PIK3CBPIK3CDPIK3CAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2604601-B1 | HETERO RING COMPOUND | ASTELLAS PHARMA INC (JP) | 2016-02-24 | — | — | EP | disclosed |