Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 4/20 | 0.51 |
| ▸ | TDP2 | O95551 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PARG | Q86W56 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17529456 | 0.84 | NPSR1 (0.56) | NPSR1PARP1TDP2MEN1KMT2A | |
| SCHEMBL17529466 | 0.82 | PARP1 (0.61) | NPSR1PARP1TDP2MEN1KMT2A | |
| SCHEMBL17529459 | 0.81 | MEN1 (0.57) | NPSR1PARP1MEN1KMT2APKM | |
| SCHEMBL17529461 | 0.79 | NPSR1 (0.54) | NPSR1PARP1TDP2MEN1KMT2A | |
| SCHEMBL17529467 | 0.73 | NPSR1 (0.54) | NPSR1PARP1MEN1KMT2APKM | |
| SCHEMBL17529463 | 0.72 | NPSR1 (0.49) | NPSR1PARP1TDP2MEN1KMT2A | |
| SCHEMBL28662829 | 0.71 | NPSR1 (0.55) | NPSR1PARP1MEN1KMT2APKM | |
| SCHEMBL57038 | 0.71 | PARP1 (1.00) | NPSR1PARP1MEN1KMT2APKM | |
| SCHEMBL2487811 | 0.71 | PARP1 (1.00) | NPSR1PARP1MEN1KMT2APKM | |
| SCHEMBL22753289 | 0.69 | CDK5 (0.45) | NPSR1PARP1TDP2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016028225-A1 | PLATINUM COMPLEXES AS ANTICANCER AGENTS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2016-02-25 | — | — | WO | disclosed |