Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 7/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1014871 | 0.95 | SERPINE1 (0.51) | SERPINE1TSHRGAAPOLBKDM4E | |
| SCHEMBL1013740 | 0.90 | SERPINE1 (0.51) | SERPINE1GAAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL1013661 | 0.89 | SERPINE1 (0.59) | SERPINE1GAAPOLBKDM4EALDH1A1 | |
| SCHEMBL1013863 | 0.87 | SERPINE1 (0.44) | SERPINE1TSHRGAAPOLBKDM4E | |
| SCHEMBL1015677 | 0.82 | KDM4E (0.44) | SERPINE1TSHRGAAPOLBKDM4E | |
| SCHEMBL1015621 | 0.82 | SERPINE1 (0.50) | SERPINE1POLBKDM4EALDH1A1HSD17B10 | |
| SCHEMBL1013719 | 0.82 | SERPINE1 (0.44) | SERPINE1GAAPOLBKDM4EALDH1A1 | |
| SCHEMBL1015571 | 0.82 | SERPINE1 (0.59) | SERPINE1TSHRGAAPOLBKDM4E | |
| SCHEMBL1013304 | 0.78 | SERPINE1 (0.59) | SERPINE1GAAPOLBKDM4EALDH1A1 | |
| SCHEMBL1014912 | 0.78 | MEN1 (0.42) | SERPINE1GAAKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2990057-A1 | NOVEL USE FOR PAI-1 INHIBITOR | Renascience Co., Ltd. (JP) | 2016-03-02 | — | — | EP | disclosed |