SCHEMBL17530709

SCHEMBL17530709

COC(=O)[C@H](Cc1ccc(-c2ccc(C#N)cc2)cc1)NC(=O)C1Cc2cc3c(cc2CN1C(=O)O)O[C@@H](c1ccc(OCc2ccc(Cl)c(Cl)n2)cc1)C(=O)N3

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1151744 0.94 GLP1R (0.53) GLP1R
SCHEMBL1151746 0.94 GLP1R (0.53) GLP1R
SCHEMBL17530733 0.92 GLP1R (0.65) GLP1R
SCHEMBL3003979 0.87 GLP1R (0.72) GLP1R
SCHEMBL3003981 0.87 GLP1R (0.72) GLP1R
SCHEMBL1151257 0.86 GLP1R (0.61) GLP1R
SCHEMBL17530751 0.86 GLP1R (0.61) GLP1R
SCHEMBL1151319 0.86 GLP1R (0.61) GLP1R
SCHEMBL1151254 0.86 GLP1R (0.61) GLP1R
SCHEMBL1151322 0.86 GLP1R (0.61) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2262364-B1 OXADIAZOANTHRACENE COMPOUNDS FOR THE TREATMENT OF DIABETES VTV THERAPEUTICS LLC (US) 2016-03-02 EP disclosed