SCHEMBL17530732

SCHEMBL17530732

COC(=O)[C@H](Cc1ccc(-c2ccc(C#N)cc2)cc1)NC(=O)C1Cc2cc3c(cc2CN1C(=O)O)O[C@@H](c1ccc(OCc2ccc(Cl)c(Cl)c2)cc1)C(=O)N3C

nearest known ligand 0.74

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 20/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1152210 0.93 GLP1R (0.69) GLP1R
SCHEMBL1151152 0.93 GLP1R (0.69) GLP1R
SCHEMBL1152213 0.93 GLP1R (0.69) GLP1R
SCHEMBL1151150 0.93 GLP1R (0.69) GLP1R
SCHEMBL12798927 0.90 GLP1R (0.76) GLP1R
SCHEMBL1151714 0.90 GLP1R (0.76) GLP1R
SCHEMBL1151715 0.90 GLP1R (0.76) GLP1R
SCHEMBL1151717 0.89 GLP1R (0.92) GLP1R
SCHEMBL1151804 0.89 GLP1R (0.92) GLP1R
SCHEMBL1152063 0.89 GLP1R (0.92) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2262364-B1 OXADIAZOANTHRACENE COMPOUNDS FOR THE TREATMENT OF DIABETES VTV THERAPEUTICS LLC (US) 2016-03-02 EP disclosed