Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 5/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | PRKCH | P24723 | 1/20 | 0.32 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17530779 | 0.91 | PIK3CD (0.36) | DPP4IRAK4PIK3CDIDH1PIK3CA | |
| SCHEMBL17530774 | 0.90 | IDH1 (0.46) | IDH1 | |
| SCHEMBL17530814 | 0.89 | DPP4 (0.37) | DPP4IRAK4PIK3CDIDH1SOS1 | |
| SCHEMBL17530857 | 0.86 | IDH1 (0.34) | PIK3CDIDH1PIK3CAMTORSOS1 | |
| SCHEMBL17530800 | 0.85 | IRAK4 (0.38) | DPP4IRAK4PIK3CDIDH1PIK3CA | |
| SCHEMBL718088 | 0.83 | PIK3CD (0.42) | PIK3CDIDH1PIK3CAMTORSOS1 | |
| SCHEMBL718089 | 0.83 | PIK3CD (0.42) | PIK3CDIDH1PIK3CAMTORSOS1 | |
| SCHEMBL15875818 | 0.82 | SOS1 (0.38) | IDH1PIK3CAMTORSOS1OPRK1 | |
| SCHEMBL15875820 | 0.82 | SOS1 (0.38) | IDH1PIK3CAMTORSOS1OPRK1 | |
| SCHEMBL17530792 | 0.82 | IDH1 (0.44) | PIK3CDIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403847-B1 | TRIAZINE DERIVATIVES AS KINASE INHIBITORS | UCB BIOPHARMA SPRL (BE) | 2016-03-02 | — | — | EP | claimed |