Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 8/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | PRKCH | P24723 | 1/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17530777 | 0.89 | PRKCH (0.35) | KDM4EALDH1A1SMN1; SMN2KMT2APRKCH | |
| SCHEMBL715531 | 0.79 | PIK3CD (0.44) | PIK3CD | |
| SCHEMBL713514 | 0.79 | PIK3CD (0.48) | PIK3CDTSHRALOX15CASP1CASP7 | |
| SCHEMBL17530807 | 0.79 | PIK3CD (0.58) | PIK3CD | |
| SCHEMBL716764 | 0.77 | PIK3CD (0.48) | PIK3CDTSHRALOX15CASP1CASP7 | |
| SCHEMBL861347 | 0.76 | PIK3CD (0.41) | PIK3CDTSHRALOX15CASP1CASP7 | |
| SCHEMBL716475 | 0.76 | PIK3CD (0.40) | PIK3CDTSHRALOX15CASP1CASP7 | |
| SCHEMBL715530 | 0.76 | PIK3CD (0.39) | PIK3CDTSHRALOX15CASP1CASP7 | |
| SCHEMBL713672 | 0.70 | KDR (0.46) | L3MBTL1KDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL716993 | 0.69 | PIK3CD (0.50) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403847-B1 | TRIAZINE DERIVATIVES AS KINASE INHIBITORS | UCB BIOPHARMA SPRL (BE) | 2016-03-02 | — | — | EP | disclosed |