SCHEMBL17530841

SCHEMBL17530841

CC(C)(C)OC(=O)ON1Cc2cc3c(cc2CC1C(=O)N[C@@H](Cc1ccc(-c2ccc(C#N)cc2)cc1)C(=O)O)NC(=O)[C@H](c1ccc(OCc2cnc(Cl)c(Cl)c2)cc1)O3

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 20/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17530734 0.94 GLP1R (0.62) GLP1R
SCHEMBL12849383 0.92 GLP1R (0.59) GLP1R
SCHEMBL1151859 0.92 GLP1R (0.59) GLP1R
SCHEMBL1151857 0.92 GLP1R (0.59) GLP1R
SCHEMBL12849226 0.88 GLP1R (0.60) GLP1R
SCHEMBL1151462 0.88 GLP1R (0.60) GLP1R
SCHEMBL1151453 0.88 GLP1R (0.60) GLP1R
SCHEMBL1151466 0.88 GLP1R (0.60) GLP1R
SCHEMBL1151457 0.88 GLP1R (0.60) GLP1R
SCHEMBL1152569 0.87 GLP1R (0.54) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2262364-B1 OXADIAZOANTHRACENE COMPOUNDS FOR THE TREATMENT OF DIABETES VTV THERAPEUTICS LLC (US) 2016-03-02 EP claimed