Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TOP2A | P11388 | 3/20 | 0.34 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20549459 | 0.85 | KDM4E (0.36) | KDM4EKMT2AALDH1A1TOP2ATOP2B | |
| SCHEMBL17529316 | 0.83 | KDM4E (0.36) | KDM4EKMT2AALDH1A1TOP2ATOP2B | |
| SCHEMBL17532920 | 0.81 | TOP2A (0.44) | KDM4EKMT2AALDH1A1TOP2ATOP2B | |
| SCHEMBL18056956 | 0.81 | TOP2A (0.44) | KDM4EKMT2AALDH1A1TOP2ATOP2B | |
| SCHEMBL16189507 | 0.81 | KDM4E (0.33) | KDM4EKMT2AALDH1A1TOP2ATOP2B | |
| SCHEMBL20549392 | 0.80 | KDM4E (0.33) | KDM4EKMT2AALDH1A1TOP2ATOP2B | |
| SCHEMBL20549449 | 0.75 | KCNH2 (0.35) | KDM4EKMT2AALDH1A1TOP2ATOP2B | |
| SCHEMBL20549376 | 0.75 | KDM4E (0.32) | KDM4EKMT2AALDH1A1TOP2ATOP2B | |
| SCHEMBL20549545 | 0.73 | KDM4E (0.39) | KDM4EKMT2AALDH1A1TOP2ATOP2B | |
| SCHEMBL18925666 | 0.71 | TOP2A (0.33) | KDM4EKMT2AALDH1A1TOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2987787-A1 | NOVEL COMPOUND WITH ANTIBACTERIAL ACTIVITY | Juntendo Educational Foundation (JP) | 2016-02-24 | — | — | EP | disclosed |